Adult stem cell
An undifferentiated cell found in a differentiated tissue that can
renew itself and (with certain limitations) differentiate to yield
all the specialized cell types of the tissue from which it originated.
Burns
Burns are classified according to the depth of the burn. In partial-thickness
burns some part of the stratum basale remains viable, and regeneration
of the epidermis occurs from within the burn area as well as from
the edges of the burn. Partial-thickness burns are divided into first-and
second-degree burns.
First-degree burns involves only the epidermis and are red
and painful, and slight edema, or swelling, can be present. They can
be caused by sunburn or brief exposure to hot or cold objects, and
they heal without scarring in about a week.
Second-degree burns damage the epidermis and the dermis. If
there is minimal dermal damage, symptomas include redness, pain, edema,
and blisters. Healing takes about 2 weeks, and there is no scarring.
If the burn goes deep into the dermis, however, the wound appears
red, tan, or white; can take several months to heal; and might scar.
In all second-degree burns, the epidermis regenerates from epithelial
tissue in hair follicles and sweat glands, as well as from the edges
of the wound.
In full-thickness, or third-degree, burns the
epidermis and the dermis are completely destroyed, and recovery occurs
from the edges of the burn wound. Third-degree burns often are surrounded
by areas of first- and second-degree burns. Although the first- and
second-degree burn areas are painful, the region of third- degree
burn is usually painless because sensory receptors in the epidermis
and dermis have been destroyed. Third-degree burns apear white, tan,
brown, black, or deep cherry red.
Deep partial-thickness and full-thickness burns take a long time to
heal, and they form scar tissue with disfiguring and debilitating
wound contracture. To prevent these complications and to speed healing,
skin grafts are often performed. In a split skin graft the epdermis
and part of the dermis are removed from another part of the body and
placed over the burn. Interstitial fluid from the burn nourishs the
graft until blood vessels grow into the graft and supply it with nourishment.
Meanwhile, the donor tissue produces new epidermis from epith epithelial
tissue in the hair follicles and sweat glands in the same manner as
in superfical second-degree burns.
BRT
Is the abbreviation of Burns Regenerative Therapy, established by
Professor Rongxiang Xu, is an innovative therapeutic system completely
different from the conventional burn management, both in concept and
in practice. This new approach is aimed at treating damaged tissue
organs in skin by potentiating and stimulating Potential Regenerative
Cells and Stem Cells in situ and thereby directly repairing and regenerating
tissues of the skin without transplantation.
Exudate
A fluid that has exuded out of a tissue or its capillaries due to
injury or inflammation.
Embryonic stem cells
Primitive (undifferentiated) cells from the embryo that have the potential
to becomea wide variety of specialized cell types.
In vitro
Literally, "in glass"; in a laboratory dish or test tube;
an artificial environment.
In situ
A Latin phrase meaning ¡°in the original location.¡± In scientific experimentation,
it refers to experiments conducted in the actual site of the phenomenon
under study, in contrast to in vitro (outside the living body and
in an artificial environment) and in vivo (in the living body of a
plant or animal).
MEBT/MEBO
Is the abbreviation of Moist Exposed Burn Therapy and Moist Exposed
Burn Ointment( a patented burn ointment), the revolutionary and practical
burn therapy invented by Prof. Xu Rongxiang, it consists of two clinical
system: the local treatment of burns wound and the systemic treatment
of burns. it contains series of theories and applied techniques. Clinically,
this therapy is carried out through MEBT and MEBO.
Potential regenerative cells (PRCs)
The special mature tissue cell discovered by Dr. Xu, which has the
potential ability to regenerate to a functional tissue similar as
stem cell but normally exists in tissue as a tissue cell. It can also
be called as the special differentiated tissue cell coming from proliferating
cell during different development stages in all types of organs in
the organism .
Stem cells
Cells with the ability to divide for indefinite periods in culture
and to give rise to specialized cells.
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